|Upper GI Digestion Model||Digestive Phase||Examine how API/Formulation affects or is affected by chemical and enzymatic processes of digestion in the upper digestive tract model|
|Mucus Permeation Model||Mucus Permeation Phase||Examine how API/Formulation permeates through mucus, and how mucus function is affected. This can be done in different conditions: Simple buffer system: Simulated intestinal fluids (without enzymes and bile); or Model digestive fluids (complete with enzymes and bile)|
|Cell Culture Systems||Epithelial Absorption Phase||Established models of gastrointestinal epithelia|
|Integrated Digestion and Mucus Permeation Model||Digestive Phase, Mucus Permeation Phase||Investigate cumulative effects of digestion and mucus permeation. Examine how API/Formulation affects or is affected by digestion, and how this goes on to effect mucus permeation and mucus function|
|Integrated Mucus Permeation and Cell Culture Models||Mucus Permeation Phase, Epithelial Absorption Phase||Investigate API/Formulation delivery across integrated model of mucus and epithelial barrier.|
|Integrated Upper GI Digestion, Mucus Permeation and Epithelial Absorption Model||Digestive Phase, Mucus Permeation Phase, Epithelial Absorption Phase||Investigate API/Formulation delivery through entire system with integrated model of digestion, mucus permeation and epithelial barrier.