What We Do
Aelius Biotech is a contract research company specialising in modelling the aero-digestive tract without the use of animal testing. Our Integrated Model Gut System is a lab model stretching from the mouth to the large intestine capable of modelling digestion, mucus permeation and absorption. We also have expertise in modelling other mucosal surfaces including the airways and access to a range of analytical services for specialised testing
Test efficacy, refine formulations, develop mechanistic data for EFSA submissions, predict and design human trials
Using a unique method for combining mucus with cell culture models allows us to simulate dissolution, mucus permeation and epithelial absorption in a single system.
Aelius Biotech systems are flexible and our scientists enjoy a challenge so if you have a sticky problem with mucus or the digestive tract, please get in touch.
From whole meals to single substrates our systems can model how your performs in a physiologically relevant simulation of digestion.
The mucus barrier acts as a key barrier to intestinal absorption. Failure to appreciate this often leads to problems with drug delivery. Our systems can simulate and predict mucus permeation.
Aelius Biotech have access to a range of standard cell lines as well as primary cell cultures from patients and normals for absorption studies.
Through close collaboration with Newcastle University we are able to offer human trials for acceptability, palatability and efficacy from pilot to large scale.
We offer competitive pricing and high quality service delivery for routine analysis and testing, along with involved follow up to help understand and interpret results..
Get in touch to see how our team of academic and industry experts can help you.
Hear from some of our previous customers how Aelius Biotech services have been able to help with product development
“Using the integrated gastric model to assess gastric damage has been very valuable to our research and development pipeline. Our interest has been in assessing the effect of our formulations on the epithelia in relevant Gl secretions with a mucus barrier present. This has been very useful to us.”
Suntory Beverage and Food (Europe)
“We have worked with Aelius Biotech on the development of two products that have gone to human trials to support EFSA health claims and have seen the value that reliable in vitro models can provide. The model has helped us make numerous key decision and investments. I am sure these models will be used by industry to accelerate and improve product development.”
Seaweed & Co.
“Working with Aelius and their human gut model proved to be an extremely cost effective way to run trials on our products. This data guided future research for human trials, as well as giving highly relevant and credible results for scientific publications and commercial successes.”
Meet our experts
Dr. Peter ChaterCEO
CEO. Peter Chater is an Innovation Fellow at Newcastle University who works on in vitro modelling of the digestive tract.
Prof. Jeff PearsonCSO
Jeff is a professor of molecular physiology with over 30 years of experience in gastrointestinal physiology.
Prof. Peter DettmarChairman
Peter has over thirty years’ experience of the pharmaceutical industry, leading gastrointestinal R&D and is a named inventor on over 40 patents.
Harvey Dettmar MBAFinance Director
Harvey Dettmar has a background in technology and investment banking and has created and worked for a number of healthcare start-up companies in finance, operations and sales..
Dr. Matt WilcoxCOO
Matt has over 10 years experience in modelling digestion at Newcastle University where he has also set up and run numerous human trials.
Kyle StanforthDevelopment Scientist.
Kyle works on developing the modelling capabilities of Aelius Biotech.
Get in touch for more information on our integrated in vitro gastrointestinal model of digestion and absorption and its relevant applications or to learn more about our innovative mucus gels suitable for modelling mucosal surfaces of the body in the lab without the need for animal models.