Colon Kit

Aelius Biotech have developed a patented ColonKit, for modelling the healthy microbiome using a sample from a single donor. The ColonKit allows multiple formulations to be analysed in parallel, in a system that models the microbiome and large intestinal mucus layer in an anaerobic environment. Test articles can be dosed directly into the model or run through our simulation of the upper digestive tract. Without disrupting the anaerobic environment, samples can be collected from the basolateral chamber to determine which compounds have permeated through the mucus and are available for epithelial absorption, or from the apical chamber to assess bacterial products or quantify changes in the bacterial population.