Mucus Modelling
Discover how the mucus layer impacts your product's performance
Mucus Modelling
The mucus layer is a crucial yet often overlooked component of human physiology. Its main function as a protective barrier to the gastrointestinal epithelia often impacts a drug's ability to cross the intestinal barrier.
Despite this, very few in vitro models account for the presence of mucus when assessing novel drugs, compounds and formulations.
How It Works
At Aelius Biotech, we have developed a model solely focused on this essential barrier. Our mucus permeation experiments are designed to assess how compounds interact with the mucus barrier and quantify which compounds will reach the epithelia for interaction and absorption. By simulating conditions of the human small intestine, we are able to assess how your formulation passes through the mucus barrier to the epithelial cells beneath.
Digestion Model
Mucus Model
Stomach (Gastric phase)
Gastric Fluids
Small intestine phase
Digestive Fluids
Analysis
- Bioavailability
- Epithelial Absorption
- Absorption Rate
- Toxicity
- Cell Damage
- Mucus Binding
- Mucus Permeation
- Carbohydrate
- Proteomics
- Amino Acid
- Sugars Analysis
- Lipid/Fatty Acid
- Benchmarking
Ready to Understand Your Product's Interactions with Mucus?
Discover how the mucus barrier affects your product's performance with our specialised modelling
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